Datasets in the Pancreatic Expression Database

View list by comparison

A set of highly relevant published pancreatic cancer papers was manually processed, data checked and results loaded into a relational database.

The data was annotated and integrated with the available Ensembl human genome annotations including gene related annotations, sequences, SNPs, gene structure, multi-species and antibody data from the human protein atlas.

We will be updating the database on a regular basis with new findings in the pancreatic cancer field. We also welcome and support pancreatic cancer scientists worldwide to deposit and share their data. If you have data that you would like to submit or any other enquiry, please email

Gene Expression study
Article Journal Title Date Volume Issue
Abe T et alJournal of GastroenterologyUpregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell deathMay-05405
Adachi J et alGenome BiologyThe human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteinsSep-0679
Akada M et alClinical Cancer ResearchIntrinsic chemoresistance to gemcitabine is associated with decreased expression of BNIP3 in pancreatic cancerApr-05118
Alhamdani MS et alJournal of ProteomicsImmunoassay-based proteome profiling of 24 pancreatic cancer cell linesJun-127512
Anderson NL et alMolecular & Cellular ProteomicsThe human plasma proteome: a nonredundant list developed by combination of four separate sourcesApr-0434
Arumugam T et alCancer ResearchEpithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic CancerJul-096914
Badea L et alHepato-GastroenterologyCombined gene expression analysis of whole-tissue and microdissected pancreatic ductal adenocarcinoma identifies genes specifically overexpressed in tumor epitheliaNov-Dec-085588
Barry S et alClinical & Experimental MetastasisS100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cellsMar-13303
Bauer AS et alPLoS ONEDiagnosis of Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis by Measurement of microRNA Abundance in Blood and TissueApr-1274
Bloomston M et alThe Journal of the Americal Medical AssociationMicroRNA Expression Patterns to Differentiate Pancreatic Adenocarcinoma From Normal Pancreas and Chronic PancreatitisMay-0729717
Buchholz M et alOncogeneTranscriptome analysis of microdissected pancreatic intraepithelial neoplastic lesionsOct-052444
Capurso G et alEndocrine-Related CancerGene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targetsJun-06132
Chaica NV et alPLoS ONEDifferential expression of metabolic genes in tumor and stromal components of primary and metastatic loci inpancreatic adenocarcinomaMar-1273
Chen R et alProteomicsQuantitative proteomic profiling of pancreatic cancer juiceJul-06613
Chen R et alPancreasComparison of Pancreas Juice Proteins from Cancer Versus Pancreatitis Using Quantitative Proteomic AnalysisJan-07341
Chen R et alGastroenterologyPancreatic cancer proteome: the proteins that underlie invasion, metastasis, and immunologic escape Oct-051294
Chen R et alMolecular & Cellular ProteomicsQuantitative proteomics analysis reveals that proteins differentially expressed in chronic pancreatitis are also frequently involved in pancreatic cancerAug-0768
Crnogorac-Jurcevic T et alGastroenterologyProteomic Analysis of Chronic Pancreatitis and Pancreatic AdenocarcinomaNov-051295
Crnogorac-Jurcevic T et alJournal of PathologyMolecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalentSep-032011
Crnogorac-Jurcevic T et alOncogeneExpression profiling of microdissected pancreatic adenocarcinomasJul-022129
Crnogorac-Jurcevic T et alOncogeneGene expression profiles of pancreatic cancer and stromal desmoplasiaNov-012050
Crnogorac-Jurcevic T et alPLoS OneMolecular analysis of precursor lesions in familial pancreatic cancerJan-1381
Donahue TR et alClinical Cancer ResearchIntegrative survival-based molecular profiling of human pancreatic cancerMar-12185
Doyle CJ et alPancreasThe proteome of normal pancreatic juiceMar-12412
Dumartin L et alCancer ResearchAGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and DNov-117122
Erkan M et alOncogeneLoss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosisJun-052427
Esposito I et alneoplasiaTumor-Suppressor Function of SPARC-Like Protein 1/Hevin in Pancreatic CancerJan-0791
Farina A et alJournal of Proteome researchA step further in the analysis of human bile proteomeApr-11104
Freiss H et alCellular and Molecular Life SciencesMicroarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancerJun-03606
Fukushima N et alOncogeneCharacterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarraysDec-042356
Fukushima N et alModern PathologyGene expression alterations in the non-neoplastic parenchyma adjacent to infiltrating pancreatic ductal adenocarcinomaJun-05186
Gadaleta E et alNucleic Acids ResearchA global insight into a cancer transcriptional space using pancreatic data: importance, findings and flawsJun-1139
Gnjatic S et alPNASSeromic profiling of ovarian and pancreatic cancerMar-1010711
Gronborg M et alJournal of Proteome ResearchComprehensive Proteomic Analysis of Human Pancreatic JuiceSep-Oct-0435
Grutzmann R et alNeoplasiaGene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarraysSep-Oct-0465
Grutzmann R et alOncogeneMeta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genesJul-052432
Hu L et alElectrophoresisTwo-dimensional protein database of human pancreasFeb-04253
Iacobuzio-Donahue CA et alThe American Journal of PathologyDiscovery of novel tumor markers of pancreatic cancer using global gene expression technologyApr-021604
Jamieson NB et alCliical Cancer ResearchMicroRNA molecular profiles associated with diagnosis, clinicopathologic criteria, and overall survival in patients with resectable pancreatic ductal adenocarcinomaJan-12182
Jimeno A et alCancer ResearchCoordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancerApr-08688
Jones S et alScienceCore signaling pathways in human pancreatic cancers revealed by global genomic analysesSep-083215897
Kakisaka T et alJournal of Chromatography BPlasma proteomics of pancreatic cancer patients by multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis (2D-DIGE): up-regulation of leucine-rich alpha-2-glycoprotein in pancreatic cancerJun-078521-2
Kanno A et alInternational Journal of CancerPeriostin, secreted from stromal cells, has biphasic effect on cell migration and correlates with the epithelial to mesenchymal transition of human pancreatic cancer cellsJun-0812212
Kosanam H et alProteomicsMining the malignant ascites proteome for pancreatic cancer biomarkersDec-111123
Lee EJ et alInternational Journal of CancerExpression profiling identifies microRNA signature in pancreatic cancerMar-071205
Li J et alMolecular CancerEnhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancerApr-0541
Logsdon CD et alCancer ResearchMolecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancerMay-036310
Lu Z et alProteomicsDifferential expression profiling of human pancreatic adenocarcinoma and healthy pancreatic tissueDec-04412
Mahon PC et alCancer ResearchS100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis inpancreatic cancerJul-076714
Maitra A et alClilical Cancer ResearchGlobal expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarraysDec-03916(1)
Makawita S et alMolecular and Cellular ProteomicsIntegrated proteomic profiling of cell line conditioned media and pancreatic juice for the identification of pancreatic cancer biomarkersOct-111010
Matsubayashi H et alCancer ResearchDNA methylation alterations in the pancreatic juice of patients with suspected pancreatic diseaseJan-15662
McKinney KQ et alCancer╩Genomics ProteomicsIdentification of differentially expressed proteins from primary versus metastatic pancreatic cancer cells using subcellular proteomicsSept-Oct-1295
Mees ST et alJournal of Surgical ResearchAnalyzing miRNAs in ductal adenocarcinomas of the pancreasAug-111692
Naidoo K et alJournal of PathologyProteome of formalin-fixed paraffin-embedded pancreatic ductal adenocarcinoma and lymph node metastasesApr-122265
Nakamura T et alOncogeneGenome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissectionMar-042313
Nakamura T et alCancer ResearchZonal heterogeneity for gene expression in human pancreatic carcinomaAug-076716
Paulo JA et alProteomics Clinical ApplicationsProteomic analysis of endoscopically (endoscopic pancreatic function test) collected gastroduodenal fluid using in-gel tryptic digestion followed by LC-MS/MSSep-1048-9
Pei H et alCancer CellFKBP51 affects cancer cell response to chemotherapy by negatively regulating AktSep-09163
Piepoli A et alPLoS ONEMirna expression profiles identity drivers in colorectal and pancreatic cancerMar-1273
Pilarsky C et alJournal of Cellular and Molecular MedicineActivation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profilingDec-08126B
Pogue-Geile KL et alPLoS MedicinePalladin mutation causes familial pancreatic cancer and suggests a new cancer mechanismDec-06312
Pogue-Geile KL et alCancer Genomics & ProteomicsA New Microarray, Enriched in Pancreas and Pancreatic Cancer cDNAs to Identify Genes Relevant to Pancreatic CancerSep-Dec-0415-6
Prasad NB et alCancer ResearchGene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cellsMar-05655
Ramachandran V et alCancer ResearchAnterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survivalOct-086819
Roldo C et alJournal of Clinical OncologyMicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behaviorOct-062429
Sato N et alThe American Journal of PathologyGene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreasMar-041643
Schiarea S et alJournal of Proteome ResearchSecretome analysis of multiple pancreatic cancer cell lines reveals perturbations of key functionalSep-1099
Segara D et alClinical Cancer ResearchExpression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasiaMay-05119
Selga E et alGenome MedicineNetworking of differentially expressed genes in human cancer cells resistant to methotrexateSep-0919
Shen J et alCancer ResearchProtein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometryDec-046424
Shi W et alMolecular and Cellular BiochemistryProteome analysis of human pancreatic cancer cell lines with highly liver metastatic potential by antibody microarrayJan-113471-2
Song D et alMolecular Cancer TherapeuticsAntitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancerOct-08710
Stratford JK et alPLoS MedicineA six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinomaJul-1077
Szafranska AE et alOncogeneMicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinomaJun-072630
Tan ZJ et alWorld Journal of GastroenterologyAnalysis of gene expression profile of pancreatic carcinoma using cDNA microarrayApr-0394
Terris B et alAmerican Journal of PathologyCharacterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreasMay-021605
Thu KL et alOncogeneSOX15 is a candidate tumor suppressor in pancreatic cancer with a potential role in Wnt/beta-catenin signalingJan-13
Van Heek NT et alCancer Biology and TherapyGene expression profiling identifies markers of ampullary adenocarcinomaJul-0437
Vimalachandran D et alCancer ResearchHigh nuclear S100A6 (Calcyclin) is significantly associated with poor survival in pancreatic cancer patientsApr-05658
Vincent A et alClinical Cancer ResearchGenome-wide analysis of promoter methylation associated with gene expression profile in pancreatic adenocarcinomaMay-111713
Wang Y et alThe Journal of Clinical InvestigationCEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cellsJun-091196
Weber JA et alClinical ChemistryThe microRNA spectrum in 12 body fluidsNov-105611
Weeks ME et alProteomics Clinical ApplicationsAnalysis of the urine proteome in patients with pancreatic ductal adenocarcinomaJul-0827-8
Whiteman HJ et alCancer ResearchThe Role of S100P in the Invasion of Pancreatic Cancer Cells Is Mediated through Cytoskeletal Changes and Regulation of Cathepsin DSep-076718
Winter C et alPLoS Computational BiologyGoogle goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genesMay-1285
Yu J et alClinical Cancer ResearchMicroRNA Alterations of Pancreatic Intraepithelial NeoplasiasFeb-12184
Yu KH et alJournal of Proteome ResearchCharacterization of proteins in human pancreatic cancer serum using differential gel electrophoresis and tandem mass spectrometrySep-Oct-0545
Zhang G et alPLoS OneDPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinomaFeb-1272
Zhang H et alProteomics Clinical ApplicationsProfiling the potential biomarkers for cell differentiation of pancreatic cancer using iTRAQ and 2-D LC-MS/MSJul-0937
Zhang L et alGastroenterologySalivary transcriptomic biomarkers for detection of resectable pancreatic cancerMar-101383
Zhang Y et alWorld Journal of SurgeryProfiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysisApr-09334
Zhou W et alJournal of Proteome researchProteomic analysis reveals Warburg effect and anomalous metabolism of glutamine in pancreatic cancer cellsFeb-12112
Copy Number Alteration study
Biankin AV et alNaturePancreatic cancer genomes reveal aberrations in axon guidance pathway genesNov-124917424
Donahue TR et alClinical Cancer ResearchIntegrative survival-based molecular profiling of human pancreatic cancerMar-12185
Harada T et alOncogeneGenome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arraysMar-082713
Jones S et alScienceCore Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic AnalysesSep-083215897
Lin LJ et alOncologyIntegrated analysis of copy number alterations and loss of heterozygosity in human pancreatic cancer using a high-resolution, single nucleotide polymorphism arraySep-08751-2
Suzuki A et alCancer ScienceIdentification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridizationMay-08995
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